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[149] Derived from Table 2 available on [150] History [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy

Are there special considerations for vitamin B12 dosing in pregnancy

Who Should Be Especially Cautious

Therefore a B12 deficiency may lead to decreased serotonin production, which in turn may cause a depressed mood

How do I know if Im B12 deficient